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The novelcoronavirusmay have already arrived in the U.S. by late December 2019 , adding to the evidence that the virus was already lurking here at least a month before the country ’s first cover event , according to a new study .
The study researchers analyse more than 24,000 blood samples collected in the U.S. from Jan. 2 to March 18 , 2020 , as part of the National Institutes of Health ’s All of Us program , a project that aims to gather health data from various population .
The researchers identified seven player from five state ( Illinois , Massachusetts , Wisconsin , Pennsylvania and Mississippi ) who prove positively charged forantibodiesagainst the novel coronavirus , SARS - CoV-2 , prior to the first reported cases of COVID-19 in those state . The early detection issue forth from a sample pull together Jan. 7 in Illinois . Because it takes about two hebdomad for a person to modernise these antibodies , the new findings paint a picture the virus may have been circulate in Illinois as early as Dec. 24 , 2019 , according to the study , publish Tuesday ( June 15 ) in the journalClinical Infectious Diseases .
" This survey allows us to unveil more information about the origin of the U.S. epidemic " of COVID-19 , Dr. Josh Denny , CEO of All of Us and co - source of the work , sound out in a command .
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The first confirmed instance of COVID-19 in the U.S. was report on Jan. 20 , 2020 , in a resident physician of Washington state who had recently move around toChina . But researchers have suspected that the virus arrive in the U.S. originally than this , and a former study from the Centers for Disease Control and Prevention also constitute evidence that the computer virus was in the U.S. in December 2019,Live Science previously reported .
Still , the new written report has limitation . Although positive antibody tests suggest a prior infection with SARS - CoV-2 , they can not examine that a person had the computer virus . For object lesson , even very accurate antibody test still bring about a modest number of false positive outcome .
But the researchers did take steps to dominate out false positives . They used two different antibody tests , and the samples had to test convinced on both to be counted as positive results . The first test identify 147 samples that were positive for SARS - CoV-2 antibodies , but of these , only nine also tested positively charged on the second test . ( Two of these sample were collected after the first cases of COVID-19 were identify in the participants ' various state . )
There ’s also a prospect that the samples had antibodies against other , like coronaviruses that " cross - react " in this test to give positive results , but this is uncommon . In 1,000 blood samples collected in the U.S. from January to March 2019 , which was used as a control condition group for comparison , none tested incontrovertible for antibodies against SARS - CoV-2 .
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" It is unbelievable all nine of these [ confirming ] individuals are faux convinced , " the generator wrote .
It ’s important to mention that the authors did not have entropy on whether the multitude who test confirming had move around recently , which would evoke whether they became septic within their communities or elsewhere . The research worker plan to follow up with the hoi polloi who tested positivist to ask about their travel story , according to The New York Times . They are also planning further research to pinpoint exactly when the novel coronavirus first appeared in the U.S.
" The exact month at which it believably came into the U.S. is still unknown , " study lead author Keri Althoff , an epidemiologist at the Johns Hopkins Bloomberg School of Public Health , enjoin the Times .
earlier published on Live Science .
